Molecular mechanisms of immunomodulatory activity of glucocorticoids

被引：91

作者：

Riccardi, C ^{[1
]}

Bruscoli, S ^{[1
]}

Migliorati, G ^{[1
]}

机构：

[1] Univ Perugia, Dept Clin & Expt Med, Sect Pharmacol Toxicol & Chemotherapy, I-06100 Perugia, Italy

来源：

PHARMACOLOGICAL RESEARCH | 2002年 / 45卷 / 05期

关键词：

glucocorticoids; immunomodulation;

D O I：

10.1006/phrs.2002.0969

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The development and function of cells in the immune system are regulated by many intrinsic and extrinsic factors. One class of molecule that affects immune cells belongs to the neuroendocrine system and the best-studied mediators in this category are glucocorticoids. These are small lypophilic molecules that participate in a wide number of normal and pathologic processes. This paper concentrates on their physiologic and pharmacologic effects on the immune response. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：361 / 368

页数：8

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