A practical, versatile difluorovinylcopper reagent

被引：27

作者：

Crowley, PJ

Howarth, JA

Owton, WM

Percy, JM

Stansfield, K

机构：

[1] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

[2] ZENECA AGROCHEM,JEALOTTS HILL RES STN,BRACKNELL RG12 6EY,BERKS,ENGLAND

[3] LILLY RES CTR LTD,WINDLESHAM GU20 6PH,SURREY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 33期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0040-4039(96)01179-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Transmetallation of an alpha-lithio-beta,beta-difluoroenol carbamate with a CuX(3)Li(2) (2LiC.Cul) produced a vinylcopper reagent that was thermally stable and reacted with activated haloalkanes and acid chlorides in moderate to high yield extending considerably the scope of building block chemistry available from trifluoroethanol. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：5975 / 5978

页数：4

共 12 条

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[8] [2,3]-Wittig rearrangements of difluoroallylic ethers. A facile entry to highly functionalized molecules containing a CF2 group
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (21) : 2509 - 2510

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