Iron-catalysed arylation of heteroaryl halides by Grignard reagents

被引:82
作者
Quintin, J [1 ]
Franck, X [1 ]
Hocquemiller, R [1 ]
Figadère, B [1 ]
机构
[1] Univ Paris Sud, CNR, BIOCIS, Lab Pharmacognosie, F-92296 Chatenay Malabry, France
关键词
D O I
10.1016/S0040-4039(02)00568-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Cross-coupling reaction of phenylmagnesium bromide with heteroaryl halides, in the presence of a catalytic amount of iron salts, is reported. Yields are moderate to good, and it is worth noting that this reaction has been applied to non-activate heteroaryl halides. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3547 / 3549
页数:3
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