Big data boost for osteoarthritis genetics

被引：6

作者：

Gonzalez, Antonio ^{[1
]}

Valdes, Ana M. ^{[2
,3
]}

机构：

[1] Hosp Clin Univ Santiago, Inst Invest Sanitaria, Expt & Observat Rheumatol, Rheumatol Unit, Santiago De Compostela, Spain

[2] Univ Nottingham, Sch Med, Acad Rheumatol, Nottingham, England

[3] Nottingham NIHR Biomed Res Ctr, Nottingham, England

来源：

NATURE REVIEWS RHEUMATOLOGY | 2018年 / 14卷 / 07期

关键词：

D O I：

10.1038/s41584-018-0023-7

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The largest study to date on the genetics of hip and knee osteoarthritis (OA) has yielded new associations with genes encoding a cytokine, a kinase and a transcriptional repressor, as well as genetic correlations with other diseases. Can these clues help to unravel details of the pathogenesis of OA?

引用

页码：387 / 388

页数：2

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