A new recirculating enzymatic membrane reactor for ester synthesis in ionic liquid/supercritical carbon dioxide biphasic systems

被引：55

作者：

Hernandez, Francisco J. ^{[1
]}

de los Rios, Antonia P. ^{[1
]}

Gomez, Demetrio ^{[1
]}

Rubio, Manuel ^{[1
]}

Villora, Gloria ^{[1
]}

机构：

[1] Univ Murcia, Fac Chem, Dept Chem Engn, E-30100 Murcia, Spain

来源：

APPLIED CATALYSIS B-ENVIRONMENTAL | 2006年 / 67卷 / 1-2期

关键词：

ionic liquids; supercritical fluids; lipase; membrane reactor;

D O I：

10.1016/j.apcatb.2006.04.009

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Dynamic membranes with immobilized Candida antarctica lipase B (CALB) were successfully applied for butyl propionate synthesis in a recirculating bioreactor in supercritical carbon dioxide medium and in room temperature ionic liquid/supercritical carbon dioxide biphasic systems at 50 degrees C and 80 bar. In room temperature ionic liquid/supercritical carbon dioxide biphasic systems, the immobilized enzyme coated with three different ionic liquids based on dialkylimidazolium cations, showed an increase in the selectivity of the process (up to 99.5%) compared with supercrifical carbon dioxide assayed in the absence of room temperature ionic liquid. For the RTILs assayed, it was observed that the increase in activity was in agreement with an increase in the partition coefficients of the substrates between RTIL and hexane. Additionally, a model based on the Ping Pong Bi-Bi mechanism with competitive alcohol inhibition is proposed to describe the kinetics of the transesterification reaction in supercrifical carbon dioxide. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：121 / 126

页数：6

共 22 条

[11] Criteria to design green enzymatic processes in ionic liquid/supercritical carbon dioxide systems [J].

Lozano, P ;

de Diego, T ;

Gmouh, S ;

Vaultier, M ;

Iborra, JL .

BIOTECHNOLOGY PROGRESS, 2004, 20 (03) :661-669

[12] Membrane reactor with immobilized Candida antarctica lipase B for ester synthesis in supercritical carbon dioxide [J].

Lozano, P ;

Víllora, G ;

Gómez, D ;

Gayo, AB ;

Sánchez-Conesa, JA ;

Rubio, M ;

Iborra, JL .

JOURNAL OF SUPERCRITICAL FLUIDS, 2004, 29 (1-2) :121-128

[13] Lipase catalysis in ionic liquids and supercritical carbon dioxide at 150°C [J].

Lozano, P ;

De Diego, T ;

Carrié, D ;

Vaultier, M ;

Iborra, JL .

BIOTECHNOLOGY PROGRESS, 2003, 19 (02) :380-382

[14] Active membranes coated with immobilized Candida antarctica lipase B:: preparation and application for continuous butyl butyrate synthesis in organic media [J].

Lozano, P ;

Pérez-Marín, AB ;

De Diego, T ;

Gómez, D ;

Paolucci-Jeanjean, D ;

Belleville, MP ;

Rios, GM ;

Iborra, JL .

JOURNAL OF MEMBRANE SCIENCE, 2002, 201 (1-2) :55-64

[15] Over-stabilization of Candida antarctica lipase B by ionic liquids in ester synthesis [J].

Lozano, P ;

De Diego, T ;

Carrié, D ;

Vaultier, M ;

Iborra, JL .

BIOTECHNOLOGY LETTERS, 2001, 23 (18) :1529-1533

[16] A new way to conduct enzymatic synthesis in an active membrane using ionic liquids as catalyst support [J].

Mori, M ;

Garcia, RG ;

Belleville, MP ;

Paolucci-Jeanjean, D ;

Sanchez, J ;

Lozano, P ;

Vaultier, M ;

Rios, G .

CATALYSIS TODAY, 2005, 104 (2-4) :313-317

[17] Kinetics of lipase-mediated synthesis of butyl butyrate in n-hexane [J].

Paiva, AL ;

van Rossum, D ;

Malcata, FX .

BIOCATALYSIS AND BIOTRANSFORMATION, 2002, 20 (01) :43-51

[18] ENZYMATIC MEMBRANE BIOREACTORS AND THEIR APPLICATIONS [J].

PRAZERES, DMF ;

CABRAL, JMS .

ENZYME AND MICROBIAL TECHNOLOGY, 1994, 16 (09) :738-750

[19] Biocatalysis in ionic liquids:: batchwise and continuous flow processes using supercritical carbon dioxide as the mobile phase [J].

Reetz, MT ;

Wiesenhöfer, W ;

Franciò, G ;

Leitner, W .

CHEMICAL COMMUNICATIONS, 2002, (09) :992-993

[20] Catalytic reactions in ionic liquids [J].

Sheldon, R .

CHEMICAL COMMUNICATIONS, 2001, (23) :2399-2407

← 1 2 3 →