The GABA(A) receptor alpha(6) subunit gene (Gabra6) is tightly linked to the alpha(1)-gamma(2) subunit cluster on mouse chromosome 11

被引：15

作者：

Garrett, KM

Haque, D

Berry, D

Niekrasz, I

Gan, JP

Rotter, A

Seale, TW

机构：

[1] UNIV OKLAHOMA,HLTH SCI CTR,DEPT PEDIAT,OKLAHOMA CITY,OK 73190

[2] OHIO STATE UNIV,DEPT PHARMACOL,COLUMBUS,OH 43210

来源：

MOLECULAR BRAIN RESEARCH | 1997年 / 45卷 / 01期

关键词：

GABA(A) receptor; alpha1; subunit; alpha6; RFLP; C57BL/6J and DBA/2J inbred strain; BXD recombinant inbred strain;

D O I：

10.1016/S0169-328X(96)00290-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have established that the GABA(A) receptor alpha(6) (Gabra6) and alpha(1) (Gabra1) subunit genes are tightly linked on mouse chromosome 11 by analyzing the strain distribution patterns of RFLPs for the two genes and microsatellite markers flanking these genes in 26 BXD recombinant inbred strains. These results further demonstrate clustering of the GABA(A) receptor subunit genes on mouse chromosomes and the synteny for these clusters between the mouse and human genomes.

引用

页码：133 / 137

页数：5

共 47 条

[1] LOCALIZATION TO CHROMOSOME-10 OF A LOCUS INFLUENCING MORPHINE ANALGESIA IN CROSSES DERIVED FROM C57BL/6 AND DBA/2 STRAINS [J].