Tools for chemical synthesis in microsystems

被引：184

作者：

Jensen, Klavs F. ^{[1
]}

Reizman, Brandon J. ^{[1
]}

Newman, Stephen G. ^{[1
]}

机构：

[1] MIT, Dept Chem Engn, Cambridge, MA 02139 USA

来源：

LAB ON A CHIP | 2014年 / 14卷 / 17期

关键词：

FLOW CHEMISTRY; MICROFLUIDIC SYSTEM; MULTISTEP SYNTHESIS; MICROREACTORS; CATALYSTS; REACTORS;

D O I：

10.1039/c4lc00330f

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Chemical synthesis in microsystems has evolved from simple proof-of-principle examples to become a general technique in academia and industry. Numerous such "flow chemistry" applications are now found in pharmaceutical and fine chemical synthesis. Much of the development has been based on systems employing macroscopic flow components and tubes, rather than the integrated chip technology envisioned by the lab-on-a-chip community. We review the major developments in systems for flow chemistry and discuss limitations underlying the development of chip-scale integrated systems.

引用

收藏

页码：3206 / 3212

页数：7

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