A review of the use and potential of the GATE Monte Carlo simulation code for radiation therapy and dosimetry applications

被引：327

作者：

Sarrut, David ^{[1
,2
,3
,4
,5
,6
]}

Bardies, Manuel ^{[7
,8
]}

Boussion, Nicolas ^{[9
]}

Freud, Nicolas ^{[10
]}

Jan, Sebastien ^{[11
]}

Letang, Jean-Michel ^{[10
]}

Loudos, George ^{[12
]}

Maigne, Lydia ^{[13
]}

Marcatili, Sara ^{[7
,8
]}

Mauxion, Thibault ^{[7
,8
]}

Papadimitroulas, Panagiotis ^{[14
]}

Perrot, Yann ^{[13
]}

Pietrzyk, Uwe ^{[15
,16
]}

Robert, Charlotte ^{[17
,18
]}

Schaart, Dennis R. ^{[19
]}

Visvikis, Dimitris ^{[9
]}

Buvat, Irene ^{[11
,17
,18
]}

机构：

[1] Univ Lyon, CREATIS, Lyon, France

[2] CNRS, UMR5220, F-75700 Paris, France

[3] INSERM, U1044, F-75654 Paris 13, France

[4] INSA Lyon, Lyon, France

[5] Univ Lyon 1, F-69622 Villeurbanne, France

[6] Ctr Leon Berard, Lyon, France

[7] INSERM, UMR1037, CRCT, F-31000 Toulouse, France

[8] Univ Toulouse 3, CRCT, UMR1037, F-31000 Toulouse, France

[9] CHU Morvan, LaTIM, UMR 1101, INSERM, F-29609 Brest, France

[10] Univ Lyon 1, CREATIS, CNRS, UMR5220,Inserm,U1044,INSA Lyon,Ctr Leon Berard, F-69008 Lyon, France

[11] CEA DSV I2BM SHFJ, F-91401 Orsay, France

[12] Technol Educ Inst Athens, Dept Med Instruments Technol, Athens 12210, Greece

[13] Univ Blaise Pascal, CNRS, IN2P3, UMR 6533, F-63171 Aubiere, France

[14] Technol Educ Inst Athens, Dept Biomed Engn, Athens 12210, Greece

[15] Forschungszentrum Julich, Inst Neurowissensch & Med, D-52425 Julich, Germany

[16] Berg Univ Wuppertal, Fachbereich Math & Naturwissensch, D-42097 Wuppertal, Germany

[17] Univ Paris 07, IMNC, CNRS, UMR 8165, F-91406 Orsay, France

[18] Univ Paris 11, IMNC, CNRS, UMR 8165, F-91406 Orsay, France

[19] Delft Univ Technol, Fac Sci Appl, Radiat Sci & Technol Dept, NL-2629 JB Delft, Netherlands

来源：

MEDICAL PHYSICS | 2014年 / 41卷 / 06期

关键词：

Monte-Carlo simulation; dosimetry; radiation therapy; DOSE-POINT KERNELS; LOW-ENERGY PHOTONS; PROTON THERAPY; IN-BEAM; INTERSEED ATTENUATION; ABSORBED FRACTIONS; QUALITY-ASSURANCE; MOUSE PHANTOM; BRACHYTHERAPY; VALIDATION;

D O I：

10.1118/1.4871617

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

100231 [临床病理学]; 100902 [航空航天医学];

摘要：

In this paper, the authors' review the applicability of the open-source GATE Monte Carlo simulation platform based on the GEANT4 toolkit for radiation therapy and dosimetry applications. The many applications of GATE for state-of-the-art radiotherapy simulations are described including external beam radiotherapy, brachytherapy, intraoperative radiotherapy, hadrontherapy, molecular radiotherapy, and in vivo dose monitoring. Investigations that have been performed using GEANT4 only are also mentioned to illustrate the potential of GATE. The very practical feature of GATE making it easy to model both a treatment and an imaging acquisition within the same framework is emphasized. The computational times associated with several applications are provided to illustrate the practical feasibility of the simulations using current computing facilities. (C) 2014 American Association of Physicists in Medicine.

引用

页数：14

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