H2O2, a necessary evil for cell signaling

被引：1807

作者：

Rhee, Sue Goo ^{[1
]}

机构：

[1] Ewha Womans Univ, Inst Mol Life Sci & Technol, Seoul 120750, South Korea

来源：

SCIENCE | 2006年 / 312卷 / 5782期

关键词：

D O I：

10.1126/science.1130481

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Once considered lethal to cells, reactive oxygen species are now known to be involved in redox signaling pathways that may contribute to normal cell function as well as disease progression.

引用

页码：1882 / 1883

页数：2

共 13 条

[1]

BIENERT GB, IN PRESS BIOCH BIOPH

[2]

*CATH U, 2006, RED SIGN HUM DIS AG

[3] Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation [J].

Chang, TS ;

Jeong, W ;

Choi, SY ;

Yu, SQ ;

Kang, SW ;

Rhee, SG .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (28) :25370-25376

[4] Intracellular reactive oxygen species activate Src tyrosine kinase during cell adhesion and anchorage-dependent cell growth [J].

Giannoni, E ;

Buricchi, F ;

Raugei, G ;

Ramponi, G ;

Chiarugi, P .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (15) :6391-6403

[5] Nox enzymes and the biology of reactive oxygen [J].

Lambeth, JD .

NATURE REVIEWS IMMUNOLOGY, 2004, 4 (03) :181-189

[6] Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes [J].

Li, QA ;

Harraz, MM ;

Zhou, WH ;

Zhang, LN ;

Ding, W ;

Zhang, YL ;

Eggleston, T ;

Yeaman, C ;

Banfi, B ;

Engelhardt, JF .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (01) :140-154

[7]

Rhee S G, 2000, Sci STKE, V2000, ppe1

[8] Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins [J].

Rhee, SG ;

Kang, SW ;

Jeong, W ;

Chang, TS ;

Yang, KS ;

Woo, HA .

CURRENT OPINION IN CELL BIOLOGY, 2005, 17 (02) :183-189

[9] REQUIREMENT FOR GENERATION OF H2O2 FOR PLATELET-DERIVED GROWTH-FACTOR SIGNAL-TRANSDUCTION [J].

SUNDARESAN, M ;

YU, ZX ;

FERRANS, VJ ;

IRANI, K ;

FINKEL, T .

SCIENCE, 1995, 270 (5234) :296-299

[10] Redox redux: Revisiting PTPs and the control of cell signaling [J].

Tonks, NK .

CELL, 2005, 121 (05) :667-670

← 1 2 →