Recognition of Mismatched Base Pairs in DNA

被引：44

作者：

Nakatani, Kazuhiko ^{[1
]}

机构：

[1] Osaka Univ, Inst Sci & Ind Res, Osaka 5670047, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2009年 / 82卷 / 09期

关键词：

GUANINE-GUANINE MISMATCHES; HUMAN TELOMERIC SEQUENCE; NAPHTHYRIDINE DIMER; HUMAN-CHROMOSOMES; MOLECULAR GLUE; BINDING; REPEAT; BULGE; FORM; POLYMORPHISM;

D O I：

10.1246/bcsj.82.1055

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mismatch binding ligand (MBL) selectively binds to mismatched base pairs with discrimination of the nucleotide bases composing the mismatch. This review focuses on the inside story regarding the molecular design of MBL and its function, and potential application in genomic science.

引用

页码：1055 / 1069

页数：15

共 68 条

[1] Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution [J].

Ambrus, Attila ;

Chen, Ding ;

Dai, Jixun ;

Bialis, Tiffanie ;

Jones, Roger A. ;

Yang, Danzhou .

NUCLEIC ACIDS RESEARCH, 2006, 34 (09) :2723-2735

[2] Trinucleotide repeat expansion and human disease [J].

Ashley, CT ;

Warren, ST .

ANNUAL REVIEW OF GENETICS, 1995, 29 :703-728

[3] Synthesis and biological properties of sequence-specific DNA-alkylating pyrrole-imidazole polyamides [J].

Bando, Toshikazu ;

Sugiyama, Hiroshi .

ACCOUNTS OF CHEMICAL RESEARCH, 2006, 39 (12) :935-944

[4] Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins [J].

Beck, JL ;

Colgrave, ML ;

Ralph, SF ;

Sheil, MM .

MASS SPECTROMETRY REVIEWS, 2001, 20 (02) :61-87

[5]

Beijer FH, 1998, ANGEW CHEM INT EDIT, V37, P75, DOI 10.1002/(SICI)1521-3773(19980202)37:1/2<75::AID-ANIE75>3.0.CO

[6]

2-R

[7] STRUCTURE AND FUNCTION OF TELOMERES [J].

BLACKBURN, EH .

NATURE, 1991, 350 (6319) :569-573

[8]

BRENOWITZ M, 1986, METHOD ENZYMOL, V130, P132

[9] Self-association without regard to prototropy. A heterocycle that forms extremely stable quadruply hydrogen-bonded dimers [J].

Corbin, PS ;

Zimmerman, SC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (37) :9710-9711

[10] Recognition of the DNA minor groove by pyrrole-imidazole polyamides [J].

Dervan, PB ;

Edelson, BS .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2003, 13 (03) :284-299

← 1 2 3 4 5 6 7 →