(2S)-2-Anilinomethylpyrrolidine:: an efficient in situ recyclable chiral catalytic source for the borane-mediated asymmetric reduction of prochiral ketones in refluxing toluene

被引：18

作者：

Basavaiah, Deevi ^{[1
]}

Rao, Kalapala Venkateswara ^{[1
]}

Reddy, Bhavanam Sekhara ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 07期

关键词：

D O I：

10.1016/j.tetasy.2006.03.021

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(2S)-2-Anilinomethylpyrrolidine was successfully utilized as a chiral catalytic source in the borane-mediated asymmetric reduction of prochiral ketones in refluxing toluene to provide the corresponding secondary alcohols with enantionteric excesses up to 91%. The potential of (2S)-2-anilinomethylpyrrolidine as an in situ recyclable chiral catalytic source in the borane-mediated chiral reduction processes has also been demonstrated. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1041 / 1044

页数：4

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