Repeats with variations:: accelerated evolution of the Pin2 farnily of proteinase inhibitors

被引：28

作者：

Barta, E ^{[1
]}

Pintar, A

Pongor, S

机构：

[1] Ctr Agr Biotechnol, H-2100 Godollo, Hungary

[2] Int Ctr Genet Engn & Biotechnol, Prot Struct & Bioinformat Grp, I-34012 Trieste, Italy

来源：

TRENDS IN GENETICS | 2002年 / 18卷 / 12期

关键词：

D O I：

10.1016/S0168-9525(02)02771-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Pin2genes encode potato type It proteinase inhibitors that art against pathogenic attack. The first examples were found only in the Solanaceaefamily, but, using new EST and genomic data, we have found 11 homologous genes dispersed through almost the whole range of mono- and di-cotyledonous plants.. In contrast to the repetitive precursor sequences of the Solanaceae Pin2genes, the new homologs have only a single repeat unit. The gene family appears to have evolved from a single-domain ancestral gene through a series of gene-duplication and domain-duplication steps. A number of unequal cross-over and gene conversion events could explain the current gene and domain pattern of the Solanaceae Pin2 subfamily.

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页码：600 / 603

页数：4

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