The aza-Wittig reaction: an efficient tool for the construction of carbon-nitrogen double bonds

被引:386
作者
Palacios, Francisco [1 ]
Alonso, Concepcion [1 ]
Aparicio, Dornitila [1 ]
Rubiales, Gloria [1 ]
de los Santos, Jesus M. [1 ]
机构
[1] Univ Basque Country, Fac Farm, Dept Quim Organ 1, Vitoria 01080, Spain
关键词
D O I
10.1016/j.tet.2006.09.048
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Recent advances in the aza-Wittig reaction of phosphazene derivatives with several carbonyl compounds are reviewed. Phosphazenes afford inter- and intramolecular aza-Wittig reactions with different compounds such as aldehydes, ketones, esters, thioesters, amides, anhydrides and sultimides. One of the most important applications of this reaction is the synthesis of a wide range of acyclic and heterocyclic compounds, ranging from simple monocyclic compounds to complex polycyclic and macrocyclic systems. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:523 / 575
页数:53
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