Magnetically Triggered Reversible Controlled Drug Delivery from Microfabricated Polymeric Multireservoir Devices

被引:76
作者
Cai, Kaiyong [1 ]
Luo, Zhong [1 ]
Hu, Yan [1 ]
Chen, Xiuyong [1 ]
Liao, Yanjian [1 ]
Yang, Li [1 ]
Deng, Linhong [1 ]
机构
[1] Chongqing Univ, Coll Bioengn, Minist Educ, Key Lab Biorheol Sci & Technol, Chongqing 400044, Peoples R China
关键词
CONTROLLED-RELEASE; MICROCHIP DEVICE; MICROSPHERES; NANOPARTICLES; MEMBRANE; SHELL;
D O I
10.1002/adma.200900593
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The pulsed reversible release of dual drugs from biodegradable polymeric multi-reservoir devices is successfully demon strated. The controlled release is achieved by incorporating magnetic particles in the devices as switch carriers. It is possible to intentionally switch on/off the drug release at any desired time for a chosen duration.
引用
收藏
页码:4045 / +
页数:6
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