Domino Palladium-Catalyzed Heck-Intermolecular Direct Arylation Reactions

被引：112

作者：

Rene, Olivier ^{[1
]}

Lapointe, David ^{[1
]}

Fagnou, Keith ^{[1
]}

机构：

[1] Univ Ottawa, Ctr Catalysis Res & Innovat, Dept Chem, Ottawa, ON K1N 6N5, Canada

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 20期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ARYL BOND FORMATION; EFFICIENT SYNTHESIS; FUNCTIONALIZATION; CYCLIZATION; ALKYL; ACTIVATION; ARENES; ACIDS;

D O I：

10.1021/ol901799p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A domino palladium-catalyzed Heck-intermolecular direct arylation reaction has been developed, giving access to a variety of dihydrobenzofurans, indolines, and oxindoles, A variety of sulfur-containing heterocycles such as thiazoles, thiophenes, and benzothiophene can be employed as the direct arylation coupling partner in yields up to 99%.

引用

页码：4560 / 4563

页数：4

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