Epigenetics and microRNAs

被引：74

作者：

Saetrom, Pal

Snove, Ola, Jr.

Rossi, John J. ^{[1
]}

机构：

[1] Beckman Res Inst City Hope, Div Mol Biol, Duarte, CA 91010 USA

[2] Interagon AS, NO-7006 Trondheim, Norway

[3] Norwegian Univ Sci & Technol, Dept Comp & Informat Sci, NO-7491 Trondheim, Norway

[4] Norwegian Univ Sci & Technol, Dept Canc Res & Mol Med, NO-7006 Trondheim, Norway

来源：

PEDIATRIC RESEARCH | 2007年 / 61卷 / 05期

关键词：

D O I：

10.1203/pdr.0b013e318045760e

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

MicroRNAs (miRNAs) regulate protein-coding genes post transcriptionally in higher eukaryotes. Argonaute proteins are important in miRNA regulation and are also implicated in epigenetic mechanisms such as histone modifications and DNA methylation. Here, we review miRNA regulation and outline its connections to epigenetics.

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页码：17R / 23R

页数：7

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