Preventing varicella-zoster disease

被引：97

作者：

Hambleton, S ^{[1
]}

Gershon, AA ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Pediat, New York, NY 10032 USA

来源：

CLINICAL MICROBIOLOGY REVIEWS | 2005年 / 18卷 / 01期

关键词：

D O I：

10.1128/CMR.18.1.70-80.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Varicella-zoster virus (VZV), the cause of chickenpox and shingles, is a pathogen in retreat following the introduction of mass vaccination in the United States in 1995. The live attenuated Oka vaccine, which is safe and immunogenic, gives good protection against both varicella and zoster in the short to medium term. It has undoubtedly been highly effective to date in reducing all forms of varicella, especially severe disease. However, the huge pool of latent wild-type virus in the population represents a continuing threat. Both the biology and the epidemiology of VZV disease suggest that new vaccination strategies will be required over time.

引用

页码：70 / +

页数：12

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