Compact multimodal adaptive-optics spectral-domain optical coherence tomography instrument for retinal imaging

被引：54

作者：

Bigelow, Chad E. ^{[1
]}

Iftimia, Nicusor V. ^{[1
]}

Ferguson, R. Daniel ^{[1
]}

Ustun, Teoman E. ^{[1
]}

Bloom, Benjamin ^{[1
]}

Hammer, Daniel X. ^{[1
]}

机构：

[1] Phys Sci Inc, Andover, MA 01810 USA

来源：

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION | 2007年 / 24卷 / 05期

关键词：

D O I：

10.1364/JOSAA.24.001327

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We have developed a compact, multimodal instrument for simultaneous acquisition of en. face quasi-confocal fundus images and adaptive-optics (AO) spectral-domain optical coherence tomography (SDOCT) cross-sectional images. The optical system including all AO and SDOCT components occupies a 60 x 60 cm breadboard that can be readily transported for clinical applications. The AO component combines a Hartmann-Shack wavefront sensor and a microelectromechanical systems-based deformable mirror to sense and correct ocular aperrations at 15 Hz with a maximum stroke of 4 mu m. A broadband superluminescent diode source provides 4 mu m depth resolution for SDOCT imaging. In human volunteer testing, we observed up to an 8 dB increase in OCT signal and a corresponding lateral resolution of < 10 mu m as a result of AO correction. (c) 2007 Optical Society of America.

引用

页码：1327 / 1336

页数：10

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