Highly regio- and stereoselective intermolecular tandem reaction to synthesize chloro-substituted 1,3-butadienes

被引：25

作者：

Huang, Jing-Mei ^{[1
]}

Dong, Yi ^{[1
]}

Wang, Xu-Xiao ^{[1
]}

Luo, Hui-Chao ^{[1
]}

机构：

[1] S China Univ Technol, Sch Chem & Chem Engn, Guangzhou 510640, Guangdong, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 07期

基金：

中国国家自然科学基金;

关键词：

TRIPTERYGIUM-WILFORDII; NATURAL-PRODUCTS; ACETYLENES;

D O I：

10.1039/b923464k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A palladium catalyzed highly regio- and stereoselective intermolecular tandem reaction of alkynes, CuCl(2) and alkenes by a sequence of chloropalladation/Heck reaction to produce chloro-substituted 1,3-dienes is achieved.

引用

页码：1035 / 1037

页数：3

共 20 条

[1] Synthesis of Two Bioactive Natural Products: FR252921 and Pseudotrienic Acid B [J].

Amans, Dominique ;

Bellosta, Veronique ;

Cossy, Janine .

CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (14) :3457-3473

[2]

BACKVALL JE, 1995, ORGANOMETALLICS, V14, P4242

[3] Libraries from natural product-like scaffolds [J].

Boldi, AM .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (03) :281-286

[4] Functionalized 1-alkoxy-1,3-dienes: Their preparation and applications in synthetic organic [J].

Deagostino, Annamaria ;

Prandi, Cristina ;

Zavattaro, Chiara ;

Venturello, Paolo .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2006, 2006 (11) :2463-2483

[5] Palladium-catalyzed allylation of alkynes with allyl alcohol in aqueous media: Highly regio and stereoselective synthesis of 1,4-dienes [J].

Huang, JM ;

Zhou, L ;

Jiang, HF .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (12) :1945-1949

[6] The chemistry and biology of the leptomycin family [J].

Kalesse, M ;

Christmann, M .

SYNTHESIS-STUTTGART, 2002, (08) :981-1003

[7] SELECTIVE CODIMERIZATION OF ACETYLENES AND ALLYL HALIDES CATALYZED BY PALLADIUM COMPLEXES [J].

KANEDA, K ;

UCHIYAMA, T ;

FUJIWARA, Y ;

IMANAKA, T ;

TERANISHI, S .

JOURNAL OF ORGANIC CHEMISTRY, 1978, 44 (01) :55-63

[8] Synthetic studies directed toward amphidinol 2: elucidation of the relative configuration of the C1-C10 fragment [J].

Kommana, Praveen ;

Chung, Seung Won ;

Donaldson, William A. .

TETRAHEDRON LETTERS, 2008, 49 (43) :6209-6211

[9]

Kutney JP, 1997, HETEROCYCLES, V44, P95

[10] Diversity oriented synthesis and branching reaction pathway to generate natural product-like compounds [J].

Liao, Y ;

Hu, YH ;

Wu, H ;

Zhu, Q ;

Donovan, M ;

Fathi, R ;

Yang, Z .

CURRENT MEDICINAL CHEMISTRY, 2003, 10 (21) :2285-2316

← 1 2 →