Analysis of 'SHENMAI' injection by HPLC/MS/MS

被引：85

作者：

Zhang, HJ ^{[1
]}

Wu, YJ ^{[1
]}

Cheng, YY ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Mat Sci & Chem Engn, Inst Pharmaceut Engn, Hangzhou 310027, Peoples R China

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2003年 / 31卷 / 01期

基金：

中国国家自然科学基金;

关键词：

SHENMAI injection; red ginseng; ginsenosides; quality control; HPLC/MS;

D O I：

10.1016/S0731-7085(02)00565-4

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An HPLC/MS/MS method was developed for the analysis of 'SHENMAI' injection, composed of red ginseng and ophiopogon. The constituents of 'SHENMAI' were found to be similar with those of ginseng and 39 ginsenosides were detected. By the studies of MS and MS/MS spectra and the comparison with literature data, most of these ginsenosides were identified. Based on this study, suggestions were put forward to improve the quality control system of 'SHENMAI' injection. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：175 / 183

页数：9

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