Spotlights on advances in mycotoxin research

被引:11
作者
Bohnert, Markus [1 ]
Wackler, Barbara [1 ]
Hoffmeister, Dirk [1 ]
机构
[1] Univ Jena, Dept Pharmaceut Biol, Hans Knoll Inst, D-07745 Jena, Germany
关键词
Ascomycetes; Basidiomycetes; Biosynthesis; Genomics; Mycotoxin; Natural products; NONRIBOSOMAL PEPTIDE SYNTHETASE; IPOMOEA-ASARIFOLIA CONVOLVULACEAE; BIOSYNTHETIC GENE CLUSTERS; POLYKETIDE SYNTHASE GENES; ACTIVATED PROTEIN-KINASE; ASPERGILLUS-NIDULANS; SECONDARY METABOLISM; FUSARIUM-GRAMINEARUM; NATURAL-PRODUCTS; GLIOTOXIN PRODUCTION;
D O I
10.1007/s00253-010-2565-8
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A remarkable feature of filamentous fungi is their ability to produce small yet structurally complex and often bioactive natural products. In this mini-review, we cover advances in the research on fungal secondary metabolites, particularly mycotoxins, and focus on biosynthetic aspects as well as on the complex regulatory mechanisms which control the expression of biosynthetic genes. We also highlight the increasing impact of genomics and transcriptomics, which help explore the realm of secondary metabolism of fungi.
引用
收藏
页码:1 / 7
页数:7
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