Tetra-ortho-Substituted Biaryls through Palladium-Catalyzed Suzuki-Miyaura Couplings with a Diaminochlorophosphine Ligand

被引：103

作者：

Ackermann, Lutz ^{[1
]}

Potukuchi, Harish K. ^{[1
]}

Althammer, Andreas ^{[1
]}

Born, Robert ^{[1
]}

Mayer, Peter ^{[2
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

[2] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 05期

关键词：

ARYL CHLORIDES; PHOSPHINOUS ACID; C-C; ARYLATIONS; PRELIGANDS; OXIDES; HALIDES; WATER; RUTHENOCENYLPHOSPHINE; ARYLSILOXANES;

D O I：

10.1021/ol1000186

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium complex derived from a sterically hindered diaminochlorophosphine allowed for Suzuki-Miyaura cross-couplings of chloroarenes with ample scope and provided access to tetra-ortho-substituted bi(hetero)aryls.

引用

页码：1004 / 1007

页数：4

共 42 条

[1] Air-stable phosphine oxides as preligands for catalytic activation reactions of C-Cl, C-F, and C-H bonds
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[2] Cross-coupling reactions of aryl and vinyl chlorides catalyzed by a palladium complex derived from an air-stable H-phosphonate
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[3] Phosphine oxides as preligands in ruthenium-catalyzed arylations via C-H bond functionalization using aryl chlorides
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[4] Modular diamino- and dioxophosphine oxides and chlorides as ligands for transition-metal-catalyzed C-C and C-N couplings with aryl chlorides
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[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (45) : 7627 - 7630
[7] Air-stable PinP(O)H as preligand for palladium-catalyzed Kumada couplings of unactivated tosylates
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[J]. ORGANIC LETTERS, 2006, 8 (16) : 3457 - 3460
[8] Air- and moisture-stable secondary phosphine oxides as preligands in catalysis
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[J]. SYNTHESIS-STUTTGART, 2006, 10 (10): : 1557 - 1571
[9] Palladium-Catalyzed Cross-Coupling Reactions of 2-Pyridylborates with Air-Stable HASPO Preligands
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[J]. SYNLETT, 2009, (17) : 2852 - 2856
[10] Air-Stable Secondary Phosphine Oxide as Preligand for Palladium-Catalyzed Intramolecular α-Arylations with Chloroarenes
Ackermann, Lutz
Vicente, Ruben
Hofmann, Nora
[J]. ORGANIC LETTERS, 2009, 11 (19) : 4274 - 4276

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