Electrolytic partial fluorination of organic compounds Part 62 - Highly diastereoselective anodic fluorination of chiral 1,3-oxathiolan-5-ones derived from camphorsulfonamides

被引：14

作者：

Baba, D

Yang, YJ

Uang, BJ

Fuchigami, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Elect Chem, Midori Ku, Yokohama, Kanagawa 2268502, Japan

[2] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2003年 / 121卷 / 01期

关键词：

anodic fluorination; asymmetric fluorination; camphorsulfonamide;

D O I：

10.1016/S0022-1139(02)00341-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Anodic fluorination of chiral 1,3-oxathiolan-5-ones, derived from camphorsulfonamide and thioglycol acid, was carried out under various conditions. When dimethoxyethane (DME) containing Et4NF.4HF was used, the corresponding monofluororinated products were obtained in good yield as a single diastereomer. Chemical fluorination was also attempted using N-fluoropyridinium salts; however, fluorination did not proceed at all. (C) 2003 Elsevier Science B.V. All rights reserved.

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页码：93 / 96

页数：4

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