Guanidine hydrochloride: An active and simple catalyst for Strecker type reaction

被引：59

作者：

Heydari, Akbar ^{[1
]}

Arefi, Afsaneh ^{[1
]}

Khaksar, Samad ^{[1
]}

Shiroodi, Roohollah Kazem ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 271卷 / 1-2期

关键词：

multicomponent reaction; Strecker reaction; guanidine hydrochloride; alpha-aminonitrile;

D O I：

10.1016/j.molcata.2007.02.046

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Commercially available guanidine hydrochloride (GuHCl) has been found to be a highly efficient catalyst for the Strecker reaction. A wide variety of aldehydes can be easily transformed into the corresponding alpha-aminonitriles using 3 mol% GuHCl within I h at 40 degrees C in methanol. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：142 / 144

页数：3

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