学术探索
学术期刊
新闻热点
数据分析
智能评审

The hormonal control of food intake

被引：441
作者：
Coll, Anthony P. [1 ]
Farooqi, I. Sadaf [1 ]
O'Rahilly, Stephen [1 ]
机构：
[1] Addenbrookes Hosp, Cambridge Inst Med Res, Dept Clin Biochem, Cambridge CB2 2XY, England
来源：
CELL | 2007年 / 129卷 / 02期
基金：
英国医学研究理事会; 英国惠康基金;
关键词：
D O I：
10.1016/j.cell.2007.04.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Numerous circulating peptides and steroids produced in the body influence appetite through their actions on the hypothalamus, the brain stem, and the autonomic nervous system. These hormones come from three major sites-fat cells, the gastrointestinal tract, and the pancreas. In this Review we provide a synthesis of recent evidence concerning the actions of these hormones on food intake.
引用
收藏
页码：251 / 262
页数：12
相关论文
共 89 条
  • [11] Induction of leptin resistance through direct interaction of C-reactive protein with leptin
    Chen, K
    Li, FH
    Li, J
    Cai, HB
    Strom, S
    Bisello, A
    Kelley, DE
    Friedman-Einat, M
    Skibinski, GA
    McCrory, MA
    Szalai, AJ
    Zhao, AZ
    [J]. NATURE MEDICINE, 2006, 12 (04) : 425 - 432
  • [12] Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice
    Chida, D
    Osaka, T
    Hashimoto, O
    Iwakura, Y
    [J]. DIABETES, 2006, 55 (04) : 971 - 977
  • [13] Choudhury AI, 2005, J CLIN INVEST, V115, P940
  • [14] Proopiomelanocortin and energy balance: Insights from human and murine genetics
    Coll, AP
    Farooqu, IS
    Challis, BG
    Yeo, GSH
    O'Rahilly, S
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2004, 89 (06) : 2557 - 2562
  • [15] Anatomy and regulation of the central melanocortin system
    Cone, RD
    [J]. NATURE NEUROSCIENCE, 2005, 8 (05) : 571 - 578
  • [16] The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
    Cowley, MA
    Smith, RG
    Diano, S
    Tschöp, M
    Pronchuk, N
    Grove, KL
    Strasburger, CJ
    Bidlingmaier, M
    Esterman, M
    Heiman, ML
    Garcia-Segura, LM
    Nillni, EA
    Mendez, P
    Low, MJ
    Sotonyi, P
    Friedman, JM
    Liu, HY
    Pinto, S
    Colmers, WF
    Cone, RD
    Horvath, TL
    [J]. NEURON, 2003, 37 (04) : 649 - 661
  • [17] Minireview: Glucocorticoids - Food intake, abdominal obesity, and wealthy nations in 2004
    Dallman, MF
    La Fleur, SE
    Pecoraro, NC
    Gomez, F
    Houshyar, H
    Akana, SF
    [J]. ENDOCRINOLOGY, 2004, 145 (06) : 2633 - 2638
  • [18] Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
    Dhillon, H
    Zigman, JM
    Ye, CP
    Lee, CE
    McGovern, RA
    Tang, VS
    Kenny, CD
    Christiansen, LM
    White, RD
    Edelstein, EA
    Coppari, R
    Balthasar, N
    Cowley, MA
    Chua, S
    Elmquist, JK
    Lowelll, BB
    [J]. NEURON, 2006, 49 (02) : 191 - 203
  • [19] Adrenalectomy alters the sensitivity of the central nervous system melanocortin system
    Drazen, DL
    Wortman, MD
    Schwartz, MW
    Clegg, DJ
    van Dijk, G
    Woods, SC
    Seeley, RJ
    [J]. DIABETES, 2003, 52 (12) : 2928 - 2934
  • [20] The biology of incretin hormones
    Drucker, DJ
    [J]. CELL METABOLISM, 2006, 3 (03) : 153 - 165
123456789