Total synthesis of analogs of topostin B, a DNA topoisomerase I inhibitor. Part 3. Improved synthesis of topostin B-1 analogs

被引：2

作者：

Fujiwara, H ^{[1
]}

Aoyama, T ^{[1
]}

Shioiri, T ^{[1
]}

机构：

[1] Nagoya City Univ, Fac Pharmaceut Sci, Mizuho Ku, Nagoya, Aichi 467, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 3-4期

关键词：

D O I：

10.1016/S0040-4020(97)10315-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Analogs or (E)-topostin B-1 (1a-c) and (Z)-topostin B-1 (2a-c), an inhibitor of mammalian DNA topoisomerase I, have been synthesized in a convenient manner. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：551 / 564

页数：14

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