Intestinal M cells and their role in bacterial infection

被引：48

作者：

Clark, MA

Jepson, MA ^{[1
]}

机构：

[1] Univ Bristol, Cell Imaging Facil, Bristol BS8 1TD, Avon, England

[2] Univ Bristol, Dept Biochem, Bristol BS8 1TD, Avon, England

[3] Newcastle Univ, Dept Physiol Sci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY | 2003年 / 293卷 / 01期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

follicle-associated epithelium; Peyer's patches; M cell; Salmonella; Yersinia;

D O I：

10.1078/1438-4221-00242

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

M cells are located in the epithelia overlying mucosa-associated lymphoid tissues such as Peyer's patches where they function as the antigen sampling cells of the mucosal immune system. Paradoxically, some pathogens exploit M cells as a route of invasion. Here we review our current knowledge of intestinal M cells with particular emphasis on the mechanisms underlying bacterial infection of these atypical epithelial cells.

引用

收藏

页码：17 / 39

页数：23

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