Raxofelast, (±)5-(acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid:: A new antioxidant to modulate the inflammatory response during ischemia-reperfusion injury and impaired wound healing

被引：8

作者：

Bitto, A. ^{[1
]}

Minutoli, L. ^{[1
]}

Squadrito, F. ^{[1
]}

Polito, F. ^{[1
]}

Altavilla, D. ^{[1
]}

机构：

[1] Univ Messina, Pharmacol Sect, Dept Expt & Clin Med & Pharmacol, AOU Policlin G Martino, I-98124 Messina, Italy

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 03期

关键词：

raxofelast; inflammation; ischemia/reperfusion injury; wound healing; diabetes; safety;

D O I：

10.2174/138955707780059835

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Raxofelast, also named IRFI 016 or (+/-)5-(Acetyloxy)-2,3-dihydro-4,6,7-trimethyl-2-benzofuranacetic acid, belongs to a family of novel molecules designed with the aim to maximize antioxidant potency of phenols related to Vitamin E (alpha-tocopherol). This review will focus on the antioxidant and radical scavenging activity of this new promising compound.

引用

页码：339 / 343

页数：5

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