The role of chromatin during transcription

被引：2687

作者：

Li, Bing

Carey, Michael

Workman, Jerry L.

机构：

[1] Stowers Med Res Inst, Kansas City, MO 64110 USA

[2] Univ Calif Los Angeles, Dept Biol Chem, David Geffen Sch Med, Los Angeles, CA 90095 USA

来源：

CELL | 2007年 / 128卷 / 04期

关键词：

D O I：

10.1016/j.cell.2007.01.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromatin structure imposes significant obstacles on all aspects of transcription that are mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated through multiple mechanisms including histone modification, chromatin remodeling, histone variant incorporation, and histone eviction. In this Review, we highlight advances in our understanding of chromatin regulation and discuss how such regulation affects the binding of transcription factors as well as the initiation and elongation steps of transcription. © 2007 Elsevier Inc. All rights reserved.

引用

页码：707 / 719

页数：13

共 134 条

[31] Myc-binding-site recognition in the human genome is determined by chromatin context
Guccione, Ernesto
Martinato, Francesca
Finocchiaro, Giacomo
Luzi, Lucilla
Tizzoni, Laura
Dall'Olio, Valentina
Zardo, Giuseppe
Nervi, Clara
Bernard, Loris
Amati, Bruno
[J]. NATURE CELL BIOLOGY, 2006, 8 (07) : 764 - U225
[32] Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates
Guermah, M
Palhan, VB
Tackett, AJ
Chait, BT
Roeder, RG
[J]. CELL, 2006, 125 (02) : 275 - 286
[33] Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning
Guillemette, B
Bataille, AR
Gévry, N
Adam, M
Blanchette, M
Robert, F
Gaudreau, L
[J]. PLOS BIOLOGY, 2005, 3 (12) : 2100 - 2110
[34] Structure and mechanism of the RNA polymerase II transcription machinery
Hahn, S
[J]. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (05) : 394 - 403
[35] NUCLEOSOME LOSS ACTIVATES YEAST DOWNSTREAM PROMOTERS INVIVO
HAN, M
GRUNSTEIN, M
[J]. CELL, 1988, 55 (06) : 1137 - 1145
[36] Promoter targeting of chromatin-modifying complexes
Hassan, AH
Neely, KE
Vignali, M
Reese, JC
Workman, JL
[J]. FRONTIERS IN BIOSCIENCE-LANDMARK, 2001, 6 : D1054 - D1064
[37] Histone acetyltransferase complexes stabilize SWI/SNF binding to promoter nucleosomes
Hassan, AH
Neely, KE
Workman, JL
[J]. CELL, 2001, 104 (06) : 817 - 827
[38] The Swi2/Snf2 bromodomain is required for the displacement of SAGA and the octamer transfer of SAGA-acetylated nucleosomes
Hassan, Ahmed H.
Awad, Salma
Prochasson, Philippe
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (26) : 18126 - 18134
[39] Assembly of variant histones into chromatin
Henikoff, S
Ahmad, K
[J]. ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2005, 21 : 133 - 153
[40] Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
Henry, KW
Wyce, A
Lo, WS
Duggan, LJ
Emre, NCT
Kao, CF
Pillus, L
Shilatifard, A
Osley, MA
Berger, SL
[J]. GENES & DEVELOPMENT, 2003, 17 (21) : 2648 - 2663

← 1 2 3 4 5 6 7 8 9 10 →