The role of chromatin during transcription

被引：2687

作者：

Li, Bing

Carey, Michael

Workman, Jerry L.

机构：

[1] Stowers Med Res Inst, Kansas City, MO 64110 USA

[2] Univ Calif Los Angeles, Dept Biol Chem, David Geffen Sch Med, Los Angeles, CA 90095 USA

来源：

CELL | 2007年 / 128卷 / 04期

关键词：

D O I：

10.1016/j.cell.2007.01.015

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromatin structure imposes significant obstacles on all aspects of transcription that are mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated through multiple mechanisms including histone modification, chromatin remodeling, histone variant incorporation, and histone eviction. In this Review, we highlight advances in our understanding of chromatin regulation and discuss how such regulation affects the binding of transcription factors as well as the initiation and elongation steps of transcription. © 2007 Elsevier Inc. All rights reserved.

引用

页码：707 / 719

页数：13

共 134 条

[11] The many HATs of transcription coactivators
Brown, CE
Lechner, T
Howe, L
Workman, JL
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (01) : 15 - 19
[12] Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
Brownell, JE
Zhou, JX
Ranalli, T
Kobayashi, R
Edmondson, DG
Roth, SY
Allis, CD
[J]. CELL, 1996, 84 (06) : 843 - 851
[13] Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities
Bruno, M
Flaus, A
Stockdale, C
Rencurel, C
Ferreira, H
Owen-Hughes, T
[J]. MOLECULAR CELL, 2003, 12 (06) : 1599 - 1606
[14] Rapid accessibility of nucleosomal DNA in yeast on a second time scale
Bucceri, Andrea
Kapitza, Kristin
Thoma, Fritz
[J]. EMBO JOURNAL, 2006, 25 (13) : 3123 - 3132
[15] The CTD code
Buratowski, S
[J]. NATURE STRUCTURAL BIOLOGY, 2003, 10 (09) : 679 - 680
[16] RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation
Carey, Michael
Li, Bing
Workman, Jerry L.
[J]. MOLECULAR CELL, 2006, 24 (03) : 481 - 487
[17] Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription
Carrozza, MJ
Li, B
Florens, L
Suganuma, T
Swanson, SK
Lee, KK
Shia, WJ
Anderson, S
Yates, J
Washburn, MP
Workman, JL
[J]. CELL, 2005, 123 (04) : 581 - 592
[18] SWI/SNF displaces SAGA-acetylated nucleosomes
Chandy, Mark
Gutierrez, Jose L.
Prochasson, Philippe
Workman, Jerry L.
[J]. EUKARYOTIC CELL, 2006, 5 (10) : 1738 - 1747
[19] A HISTONE-BINDING PROTEIN, NUCLEOPLASMIN, STIMULATES TRANSCRIPTION FACTOR-BINDING TO NUCLEOSOMES AND FACTOR-INDUCED NUCLEOSOME DISASSEMBLY
CHEN, H
LI, BY
WORKMAN, JL
[J]. EMBO JOURNAL, 1994, 13 (02) : 380 - 390
[20] A NUCLEOSOME CORE IS TRANSFERRED OUT OF THE PATH OF A TRANSCRIBING POLYMERASE
CLARK, DJ
FELSENFELD, G
[J]. CELL, 1992, 71 (01) : 11 - 22

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