Monolithic chiral stationary phases for liquid-phase enantioseparation techniques

被引：61

作者：

Chankvetadze, Bezhan ^{[1
]}

机构：

[1] Tbilisi State Univ, Sch Exact & Nat Sci, Dept Phys & Analyt Chem, GE-0179 Tbilisi, Georgia

来源：

JOURNAL OF SEPARATION SCIENCE | 2010年 / 33卷 / 03期

基金：

美国国家科学基金会;

关键词：

Chromatography; Electrochromatography; Monolithic chiral stationary phases; Separation of enantiomers; EXCHANGE CAPILLARY ELECTROCHROMATOGRAPHY; SILICA COLUMNS; CELLULOSE TRIS(3,5-DIMETHYLPHENYLCARBAMATE); CHROMATOGRAPHIC ENANTIOSEPARATIONS; ENANTIOMER SEPARATION; AMINO-ACIDS; QUINIDINE FUNCTIONALITY; CONTINUOUS BEDS; PERFORMANCE; LIGAND;

D O I：

10.1002/jssc.200900805

中图分类号：

O65 [分析化学];

学科分类号：

070302 [分析化学];

摘要：

This short overview summarizes the development in the field of enantioselective monolithic chromatographic media and their application for pressure-driven and electrokinetic separations The major emphasis is put on the currently existing problems and the author's vision for their solution is provided Due to the author's personal experience silica-based monoliths are discussed in mote detail although the key developments in the field of organic monolithic materials for separation of enantiomers ate also discussed

引用

收藏

页码：305 / 314

页数：10

相关论文

共 67 条

[1]

FLOW-THROUGH PARTICLES FOR THE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF BIOMOLECULES - PERFUSION CHROMATOGRAPHY [J].

AFEYAN, NB ;

GORDON, NF ;

MAZSAROFF, I ;

VARADY, L ;

FULTON, SP ;

YANG, YB ;

REGNIER, FE .

JOURNAL OF CHROMATOGRAPHY, 1990, 519 (01) :1-29

[2]

Enantioselective catalysis and analysis on a chip [J].

Belder, D ;

Ludwig, M ;

Wang, LW ;

Reetz, MT .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (15) :2463-2466

[3]

Evaluation of a monolithic epoxy silica support for penicillin G acylase immobilization [J].

Calleri, E ;

Massolini, G ;

Lubda, D ;

Temporini, C ;

Loiodice, F ;

Caccialanza, G .

JOURNAL OF CHROMATOGRAPHY A, 2004, 1031 (1-2) :93-100

[4]

Trends in the development of chiral drugs [J].

Caner, H ;

Groner, E ;

Levy, L ;

Agranat, I .

DRUG DISCOVERY TODAY, 2004, 9 (03) :105-110

[5]

High-performance liquid chromatographic enantioseparations on capillary columns containing monolithic silica modified with amylose tris(3,5-dimethylphenylcarbamate) [J].

Chankvetadze, B ;

Yamamoto, C ;

Kamigaito, M ;

Tanaka, N ;

Nakanishi, K ;

Okamoto, Y .

JOURNAL OF CHROMATOGRAPHY A, 2006, 1110 (1-2) :46-52

[6]

High-performance liquid chromatographic enantioseparations on capillary columns containing monolithic [J].

Chankvetadze, B ;

Yamamoto, C ;

Tanaka, N ;

Nakanishi, K ;

Okamoto, Y .

JOURNAL OF SEPARATION SCIENCE, 2004, 27 (10-11) :905-911

[7]

Very fast enantioseparation in high-performance liquid chromatography using cellulose tris(3,5-dimethylphenylcarbamate) coated on monolithic silica support [J].

Chankvetadze, B ;

Yamamoto, C ;

Okamoto, Y .

CHEMISTRY LETTERS, 2003, 32 (09) :850-851

[8]

High-performance liquid chromatographic enantio separations on monolithic silica columns containing a covalently attached 3,5-dimethylphenylcarbamate derivative of cellulose [J].

Chankvetadze, B ;

Ikai, T ;

Yamamoto, C ;

Okamoto, Y .

JOURNAL OF CHROMATOGRAPHY A, 2004, 1042 (1-2) :55-60

[9]

High-performance liquid chromatographic enantioseparations on capillary columns containing crosslinked polysaccharide phenylcarbamate derivatives attached to monolithic silica [J].

Chankvetadze, Bezhan ;

Kubota, Takateru ;

Ikai, Tomoyuki ;

Yamamoto, Chiyo ;

Kamigaito, Masami ;

Tanaka, Nobuo ;

Nakanishi, Kazuki ;

Okamoto, Yoshio .

JOURNAL OF SEPARATION SCIENCE, 2006, 29 (13) :1988-1995

[10]

Electrochromatographic enantioseparation using chiral ligand exchange monolithic sol-gel column [J].

Chen, Z ;

Nishiyama, T ;

Uchiyama, K ;

Hobo, T .

ANALYTICA CHIMICA ACTA, 2004, 501 (01) :17-23

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