Integration of four genes, a pseudogene, thirty-one STSs, and a highly polymorphic STRP into the 7-10 Mb YAC contig of 5q34-q35

被引：8

作者：

Kostrzewa, M

Grady, DL

Moyzis, RK

Floter, L

Muller, U

机构：

[1] UNIV GIESSEN,INST HUMAN GENET,D-35392 GIESSEN,GERMANY

[2] LOS ALAMOS NATL LAB,CTR HUMAN GENOME STUDIES,LOS ALAMOS,NM 87545

来源：

HUMAN GENETICS | 1996年 / 97卷 / 03期

关键词：

D O I：

10.1007/s004390050060

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Thirty-one sequence tagged sites and a highly polymorphic short tandem repeat polymorphism have been isolated from 5q34-q35 and integrated into the yeast artificial chromosome (YAC) contig of 5q34-q35. In addition, four genes (MSX2, CSX, DRD1, and CL100) and a pseudogene (GLUT6) were localized on this map. The high density of new markers in the region allowed further refinement of the YAC contig of distal 5q. This is a prerequisite for the conversion of this YAC into a cosmid contig.

引用

收藏

页码：399 / 403

页数：5

相关论文

共 18 条

[1] DETECTION OF 4 POLYMORPHIC SITES IN THE HUMAN DOPAMINE D1 RECEPTOR GENE (DRD1) [J].

CICHON, S ;

NOTHEN, MM ;

ERDMANN, J ;

PROPPING, P .

HUMAN MOLECULAR GENETICS, 1994, 3 (01) :209-209

[2]

DIXON J, 1994, AM J HUM GENET, V55, P372

[3]

DOGGETT NA, 1995, NATURE, V377, P335

[4] THE DIASTROPHIC DYSPLASIA GENE ENCODES A NOVEL SULFATE TRANSPORTER - POSITIONAL CLONING BY FINE-STRUCTURE LINKAGE DISEQUILIBRIUM MAPPING [J].

HASTBACKA, J ;

DELACHAPELLE, A ;

MAHTANI, MM ;

CLINES, G ;

REEVEDALY, MP ;

DALY, M ;

HAMILTON, BA ;

KUSUMI, K ;

TRIVEDI, B ;

WEAVER, A ;

COLOMA, A ;

LOVETT, M ;

BUCKLER, A ;

KAITILA, I ;

LANDER, ES .

CELL, 1994, 78 (06) :1073-1087

[5] A MUTATION IN THE HOMEODOMAIN OF THE HUMAN MSX2 GENE IN A FAMILY AFFECTED WITH AUTOSOMAL-DOMINANT CRANIOSYNOSTOSIS [J].

JABS, EW ;

MULLER, U ;

LI, X ;

MA, L ;

LUO, W ;

HAWORTH, IS ;

KLISAK, I ;

SPARKES, R ;

WARMAN, ML ;

MULLIKEN, JB ;

SNEAD, ML ;

MAXSON, R .

CELL, 1993, 75 (03) :443-450

[6] 2.6 MB YAC CONTIG OF THE HUMAN-X INACTIVATION CENTER REGION IN XQ13 - PHYSICAL LINKAGE OF THE RPS4X, PHKA1, XIST AND DXS128E GENES [J].

LAFRENIERE, RG ;

BROWN, CJ ;

RIDER, S ;

CHELLY, J ;

TAILLONMILLER, P ;

CHINAULT, AC ;

MONACO, AP ;

WILLARD, HF .

HUMAN MOLECULAR GENETICS, 1993, 2 (08) :1105-1115

[7] A YAC CONTIG OF APPROXIMATELY 3 MB FROM HUMAN-CHROMOSOME 5Q31 -] Q33 [J].

LI, X ;

WISE, CA ;

LEPASLIER, D ;

HAWKINS, AL ;

GRIFFIN, CA ;

PITTLER, SJ ;

LOVETT, M ;

JABS, EW .

GENOMICS, 1994, 19 (03) :470-477

[8] CONSTRUCTION OF A YAC CONTIG AND A STS MAP SPANNING AT LEAST 7 MEGABASEPAIRS IN CHROMOSOME-5Q34-35 [J].

LUKUO, JM ;

LEPASLIER, D ;

WEISSENBACH, J ;

CHUMAKOV, I ;

COHEN, D ;

WARD, DC .

HUMAN MOLECULAR GENETICS, 1994, 3 (01) :99-106

[9]

MCKUSICK VM, 1995, ONLINE MENDELIAN INH

[10]

MEMSLIE EA, 1994, HUM GENET, V93, P513