On the preparation of carbamoylsilanes

被引：51

作者：

Cunico, RF ^{[1
]}

Chen, JX ^{[1
]}

机构：

[1] No Illinois Univ, Dept Chem & Biochem, De Kalb, IL 60115 USA

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 11期

关键词：

carbamoylsilane; metalation-silylation; amides; lithiation; coupling;

D O I：

10.1081/SCC-120020211

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various N,N-disubstituted carbamoyltrimethylsilanes can be prepared by the addition of LDA to a mixture of TMSCl and the appropriate formamide in THF at -78degreesC. Slow (syringe pump) addition of LDA is crucial to obtaining good yields.

引用

页码：1963 / 1968

页数：6

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