Electronic Aptamer-based Biosensor for Multiprotein Analytes on a Single Paltform

被引：4

作者：

Hayashi, Eriko ^{[1
]}

Takada, Tadao ^{[1
]}

Nakamura, Mitsunobu ^{[1
]}

Yamana, Kazushige ^{[1
]}

机构：

[1] Univ Hyogo, Dept Mat Sci & Chem, Himeji, Hyogo 6712201, Japan

来源：

CHEMISTRY LETTERS | 2010年 / 39卷 / 05期

关键词：

ELECTROCHEMICAL BIOSENSOR; SENSORS; PROTEIN; ARRAYS; PROBE;

D O I：

10.1246/cl.2010.454

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe an approach to the development of a new electronic aptamer-based biosensor for multiprotein targets on a single platform. The multiple protein biosensing involves the co-adsorption of several thiol-terminated capture DNA sequences on a gold surface, along with the hybridization of redox-tagged aptamer to each corresponding capture sequences on the electrode, addition of target proteins, and monitoring aptamer-strand release through electrochemical measurement.

引用

页码：454 / 455

页数：2

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