Mild and selective reduction of imines: Formation of an unsymmetrical macrocycle

被引：44

作者：

Gallant, AJ ^{[1
]}

Patrick, BO ^{[1
]}

MacLachlan, MJ ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 25期

关键词：

D O I：

10.1021/jo049197u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

During investigations of 5, a [3 + 3] Schiff-base macrocycle with six imines, a partially reduced Schiff-base macrocycle, 6, possessing one CH2NH and five imine groups was obtained. Control experiments and deuterium labeling indicate that the macrocycle is reduced by a benzimidazoline generated during the reaction. Benzimidazolines may be convenient reagents for the mild and selective reduction of imines.

引用

页码：8739 / 8744

页数：6

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