Regulation of plasmacytoid dendritic cell development

被引：88

作者：

Reizis, Boris ^{[1
]}

机构：

[1] Columbia Univ, Med Ctr, Dept Microbiol & Immunol, New York, NY 10032 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2010年 / 22卷 / 02期

关键词：

INTERFERON-PRODUCING CELLS; I INTERFERON; PREDENDRITIC CELLS; CUTTING EDGE; FACTOR E2-2; EXPRESSION; PRECURSORS; PROGENITORS; ACTIVATION; SUBSETS;

D O I：

10.1016/j.coi.2010.01.005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Plasmacytoid dendritic cells (PDC) represent a distinct immune cell type specialized in direct virus recognition and rapid secretion of type I interferon. The origin and lineage affiliation of PDC have been controversial, partly because PDC show features of both lymphocytes and dendritic cells (DC). Recent studies helped elucidate the cellular and molecular basis of PDC development. In particular, the common developmental origin and genetic similarity of PDC and classical antigen-presenting DC have been established. In addition, E protein transcription factor E2-2 was shown to control lineage commitment and gene expression program of PDC. Because E proteins are essential regulators of lymphocyte development, E2-2 activity may underlie the distinct 'lymphoid' features of PDC.

引用

页码：206 / 211

页数：6

共 54 条

[1] Ikaros is required for plasmacytoid dendritic cell differentiation [J].

Allman, David ;

Dalod, Marc ;

Asselin-Paturel, Carine ;

Delale, Thomas ;

Robbins, Scott H. ;

Trinchieri, Giorgio ;

Biron, Christine A. ;

Kastner, Philippe ;

Chan, Susan .

BLOOD, 2006, 108 (13) :4025-4034

[2] CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation [J].

Auffray, Cedric ;

Fogg, Darin K. ;

Narni-Mancinelli, Emilie ;

Senechal, Brigitte ;

Trouillet, Celine ;

Saederup, Noah ;

Leemput, Julia ;

Bigot, Karine ;

Campisi, Laura ;

Abitbol, Marc ;

Molina, Thierry ;

Charo, Israel ;

Hume, David A. ;

Cumano, Ana ;

Lauvau, Gregoire ;

Geissmann, Frederic .

JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (03) :595-606

[3] Sampling and signaling in plasmacytoid dendritic cells: the potential roles of Siglec-H [J].

Blasius, Amanda L. ;

Colonna, Marco .

TRENDS IN IMMUNOLOGY, 2006, 27 (06) :255-260

[4] BDCA2/FcεRlγ complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells [J].

Cao, Wei ;

Zhang, Li ;

Rosen, David B. ;

Bover, Laura ;

Watanabe, Gokuran ;

Bao, Musheng ;

Lanier, Lewis L. ;

Liu, Yong-Jun .

PLOS BIOLOGY, 2007, 5 (10) :2190-2200

[5] Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction [J].

Cao, Wei ;

Bover, Laura ;

Cho, Minkwon ;

Wen, Xiaoxia ;

Hanabuchi, Shino ;

Bao, Musheng ;

Rosen, David B. ;

Wang, Yi-Hong ;

Shaw, Joanne L. ;

Du, Qiumei ;

Li, Chun ;

Arai, Naoko ;

Yao, Zhengbin ;

Lanier, Lewis L. ;

Liu, Yong-Jun .

JOURNAL OF EXPERIMENTAL MEDICINE, 2009, 206 (07) :1603-1614

[6] Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3) K-mTOR-p70S6K pathway [J].

Cao, Weiping ;

Manicassamy, Santhakumar ;

Tang, Hua ;

Kasturi, Sudhir Pai ;

Pirani, Ali ;

Murthy, Niren ;

Pulendran, Bali .

NATURE IMMUNOLOGY, 2008, 9 (10) :1157-1164

[7] Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development [J].

Cisse, Babacar ;

Caton, Michele L. ;

Lehner, Manfred ;

Maeda, Takahiro ;

Scheu, Stefanie ;

Locksley, Richard ;

Holmberg, Dan ;

Zweier, Christiane ;

den Hollander, Nicolette S. ;

Kant, Sarina G. ;

Holter, Wolfgang ;

Rauch, Anita ;

Zhuang, Yuan ;

Reizis, Boris .

CELL, 2008, 135 (01) :37-48

[8] Plasmacytoid dendritic cells in immunity [J].

Colonna, M ;

Trinchieri, G ;

Liu, YJ .

NATURE IMMUNOLOGY, 2004, 5 (12) :1219-1226

[9] The lymphoid past of mouse plasmacytoid cells and thymic dendritic cells [J].

Corcoran, L ;

Ferrero, I ;

Vremec, D ;

Lucas, K ;

Waithman, J ;

O'Keeffe, M ;

Wu, L ;

Wilson, A ;

Shortman, K .

JOURNAL OF IMMUNOLOGY, 2003, 170 (10) :4926-4932

[10] The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3 [J].

D'Amico, A ;

Wu, L .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 198 (02) :293-303

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