[3+2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor

被引：116

作者：

Smith, Christopher D.

Baxendale, Ian R.

Lanners, Steve

Hayward, John J.

Smith, Stephen C.

Ley, Steven V.

机构：

[1] Univ Cambridge, Dept Chem, Innovat Technol Ctr, ACS, Cambridge CB2 1EW, England

[2] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2007年 / 5卷 / 10期

关键词：

D O I：

10.1039/b702995k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cycloaddition of acetylenes with azides to give the corresponding 1,4-disubstituted 1,2,3-triazoles is reported using immobilised reagents and scavengers in pre-packed glass tubes in a modular flow reactor.

引用

页码：1559 / 1561

页数：3

共 32 条

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