Gold-catalyzed efficient preparation of linear α-iodoenones from propargylic acetates

被引:152
作者
Yu, Meng [1 ]
Zhang, Guozhu [1 ]
Zhang, Liming [1 ]
机构
[1] Univ Nevada, Dept Chem, Reno, NV 89557 USA
关键词
D O I
10.1021/ol070637o
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Only 2 mol % of Au( PPh3) NTf2 is needed to convert readily accessible propargylic acetates into versatile linear alpha-iodoenones in good to excellent yields. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of aliphatic propargylic acetates derived from aldehydes.
引用
收藏
页码:2147 / 2150
页数:4
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