Allyloxycarbonyl - a useful protecting group for phenolic amino acids and applications on solid support

被引：5

作者：

Morley, AD ^{[1
]}

机构：

[1] Aventis Pharma Ltd, Dagenham RM10 7XS, Essex, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 38期

关键词：

solid-phase synthesis; protecting group; amino acids and derivatives;

D O I：

10.1016/S0040-4039(00)01263-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bis-protection of phenolic amino acids can be achieved in a one-pot procedure using allyl chloroformate. Subsequent immobilisation via the free acid onto solid support then permits the carbonate protecting group to be selectively removed under mild conditions. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7401 / 7404

页数：4

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