Comparative genomics: Genome-wide analysis in metazoan eukaryotes

被引：156

作者：

Ureta-Vidal, A ^{[1
]}

Ettwiller, L ^{[1
]}

Birney, E ^{[1
]}

机构：

[1] EMBL European Bioinformat Inst, Cambridge CB10 1SD, England

来源：

NATURE REVIEWS GENETICS | 2003年 / 4卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1038/nrg1043

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The increasing number of complete and nearly complete metazoan genome sequences provides a significant amount of material for large-scale comparative genomic analysis. Finding new effective methods to analyse such enormous datasets has been the object of intense research. Three main areas in comparative genomics have recently shown important developments: whole-genome alignment, gene prediction and regulatory-region prediction. Each of these areas improves the methods of deciphering long genomic sequences and uncovering what lies hidden in them.

引用

页码：251 / 262

页数：12

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