Unexpected addition of methyl 3,3,3-trifluoropyruvate to "push-pull' enamines having a methyl group at α-position

被引：15

作者：

Volochnyuk, DM ^{[1
]}

Kostyuk, AN ^{[1
]}

Sibgatulin, DA ^{[1
]}

Petrenko, AE ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Organ Chem, UA-02094 Kiev 94, Ukraine

来源：

SYNTHESIS-STUTTGART | 2004年 / 15期

关键词：

'push-pull' enamines; methyl 3,3,3-trifluoropyruvate; nucleophilic addition; ene reaction;

D O I：

10.1055/s-2004-831216

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of 'push-pull' enamines having a methyl group at the alpha-position with methyl 3,3,3-trifluoropyruvate was investigated. As a result, unexpected addition of pyruvate to methyl group was found and a set of polyfunctionalized beta-dicarbonyl compounds was obtained. Possible mechanism of the reaction is discussed.

引用

页码：2545 / 2549

页数：5

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