A DNA nanomachine based on a duplex-triplex transition

被引：152

作者：

Chen, Y ^{[1
]}

Lee, SH ^{[1
]}

Mao, C ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 40期

关键词：

acidity; DNA structures; DNA; molecular devices; self-assembly;

D O I：

10.1002/anie.200460789

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Making DNA work: A DNA nanomachine with a mechanism based on a DNA duplex-triplex transition (see figure) was constructed. The key component is a DNA triplex that contains C+GC triplets and is only stable under acidic conditions. The DNA machine uses H+ and OH- ions as fuel and its only waste products are H2O and NaCl.

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收藏

页码：5335 / 5338

页数：4

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