DNA origami: Fold, stick, and beyond

被引:119
作者
Kuzuya, Akinori [1 ]
Komiyama, Makoto [1 ]
机构
[1] Univ Tokyo, Adv Sci & Technol Res Ctr, Meguro Ku, Tokyo 1538904, Japan
关键词
PATTERNED SURFACES; NANOSCALE SHAPES; PROTEIN; TILES; NANOTECHNOLOGY; NANOARRAYS; MOLECULES; LATTICES; DESIGN;
D O I
10.1039/b9nr00246d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA origami is the process in which long single-stranded DNA molecules are folded into arbitrary planar nanostructures with the aid of many short staple strands. Since its initial introduction in 2006, DNA origami has dramatically widened the scope of applications of DNA nanotechnology based on the programmed assembly of branched DNA junctions. DNA origami can be used to construct not only arbitrary two-dimensional nanostructures but also nano-sized breadboards for the arraying of nanomaterials or even complicated three-dimensional nano-objects. In this review, we briefly look through the basic designs and applications of DNA origami and discuss the future of this technique.
引用
收藏
页码:310 / 322
页数:13
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