Ribosome synthesis meets the cell cycle

被引:124
作者
Dez, C [1 ]
Tollervey, D [1 ]
机构
[1] Univ Edinburgh, Wellcome Trust Ctr Cell Biol, Edinburgh EH9 3JR, Midlothian, Scotland
基金
英国惠康基金;
关键词
D O I
10.1016/j.mib.2004.10.007
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A large number of ribosome synthesis factors have been identified using proteomic analyses in yeast. The patterns of RNA and protein co-precipitation suggest that ribosome synthesis does not proceed via a linear progression of successive steps. Recent analyses have identified several interactions between factors clearly implicated in ribosome synthesis and specific steps in the cell division cycle. The intersections between these pathways were not anticipated, but potential explanations for their existence can be advanced.
引用
收藏
页码:631 / 637
页数:7
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