Signal-triggered transmembrane ion transport through synthetic channels

被引：42

作者：

Hector, RS ^{[1
]}

Gin, MS ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

来源：

SUPRAMOLECULAR CHEMISTRY | 2005年 / 17卷 / 1-2期

关键词：

synthetic ion channels; gated ion channels; ion channel sensors;

D O I：

10.1080/10610270412331328871

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This review discusses recent advances in mimicry of transmembrane ion channel proteins using artificial systems. While modified protein channels and surface-functionalized nanoporous membranes are covered briefly, the primary focus is on synthetic ion channels that have been modified to introduce signal-responsive activity. Examples are presented wherein transmembrane ion transport occurs in response to irradiation, changes in transmembrane voltage, or the presence of additives that either promote assembly or block the pore.

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页码：129 / 134

页数：6

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