Intravascular Photoacoustic Imaging

被引：90

作者：

Wang, Bo ^{[1
]}

Su, Jimmy L. ^{[1
]}

Karpiouk, Andrei B. ^{[1
]}

Sokolov, Konstantin V. ^{[1
,2
]}

Smalling, Richard W. ^{[3
,4
]}

Emelianov, Stanislav Y. ^{[1
]}

机构：

[1] Univ Texas Austin, Dept Biomed Engn, Austin, TX 78712 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Imaging Phys, Houston, TX 77030 USA

[3] Univ Texas Hlth Sci Ctr, Div Cardiol, Houston, TX 77030 USA

[4] Mem Hermann Heart & Vasc Inst, Houston, TX 77024 USA

来源：

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS | 2010年 / 16卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Atherosclerosis; contrast agent; imaging catheter; intravascular photoacoustic (IVPA) imaging; intravascular ultrasound (IVUS) imaging; molecular imaging; stent; vulnerable plaque; OPTICAL-COHERENCE-TOMOGRAPHY; GOLD NANORODS; ULTRASOUND; PLAQUE; SPECTROSCOPY; CONTRAST;

D O I：

10.1109/JSTQE.2009.2037023

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Intravascular photoacoustic (IVPA) imaging is a catheter-based, minimally invasive, imaging modality capable of providing high-resolution optical absorption map of the arterial wall. Integrated with intravascular ultrasound (IVUS) imaging, combined IVPA and IVUS imaging can be used to detect and characterize atherosclerotic plaques building up in the inner lining of an artery. In this paper, we present and discuss various representative applications of combined IVPA/IVUS imaging of atherosclerosis, including assessment of the composition of atherosclerotic plaques, imaging of macrophages within the plaques, and molecular imaging of biomarkers associated with formation and development of plaques. In addition, imaging of coronary artery stents using IVPA and IVUS imaging is demonstrated. Furthermore, the design of an integrated IVUS/IVPA imaging catheter needed for in vivo clinical applications is discussed.

引用

页码：588 / 599

页数：12

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