Antitubercular dihydroagarofuranoid sesquiterpenes from the roots of Microtropis fokienensis

被引：42

作者：

Chen, Jih-Jung ^{[1
]}

Chou, Tsung-Hsien

Peng, Chien-Fang

Chen, Ih-Sheng

Yang, Sheng-Zehn

机构：

[1] Tajen Univ, Grad Inst Pharmaceut Technol, Pingtung 907, Taiwan

[2] Kaohsiung Med Univ, Coll Pharm, Grad Inst Pharmaceut Sci, Kaohsiung 807, Taiwan

[3] Kaohsiung Med Univ, Fac Biomed Lab Sci, Coll Hlth Sci, Kaohsiung 807, Taiwan

[4] Natl Pingtung Univ Sci & Technol, Dept Forest Resource, Pingtung 912, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 02期

关键词：

D O I：

10.1021/np060500r

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new dihydroagarofuranoid sesquiterpenes (1-4) and a new hydroxybenzylsalicylaldehyde, forkienin (5), together with nine known compounds have been isolated from the roots of Microtropis fokienensis. The structures of the new compounds were determined through analyses of physical data. Compounds 3, 4, 7, and 8 exhibited potent antitubercular activities (MICs <= 26.0 mu M) against Mycobacterium tuberculosis 90-221387 in vitro.

引用

页码：202 / 205

页数：4

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