A Simple and Efficient Approach to the Synthesis of 2-Phenylquinazolines via sp3 C-H Functionalization

被引：220

作者：

Zhang, Jintang

Zhu, Dapeng

Yu, Chenmin

Wan, Changfeng

Wang, Zhiyong ^{[1
]}

机构：

[1] Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 12期

关键词：

QUINAZOLINE; BOND; QUINOLINE;

D O I：

10.1021/ol100954x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and novel approach to the synthesis of 2-phenylquinazolines was developed via a tandem reaction following sp(3) C-H functionalization. Twenty-five examples of 2-phenylquinazolines were obtained from easily available 2-aminobenzophenones and benzylic amines with good to excellent yields.

引用

页码：2841 / 2843

页数：3

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