The changing face of ciguatera

被引：257

作者：

Lewis, RJ ^{[1
]}

机构：

[1] Univ Queensland, Queensland Agr Biotechnol Ctr DPI, Gehrmann Labs, St Lucia, Qld 4072, Australia

来源：

TOXICON | 2001年 / 39卷 / 01期

关键词：

ciguatoxin; distribution; symptoms; treatment; structures; avoidence; milestones;

D O I：

10.1016/S0041-0101(00)00161-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Ciguatera is a global disease caused by the consumption of certain warm-water fish (ciguateric fish) that have accumulated orally effective levels of sodium channel activator toxins (ciguatoxins) through the marine food chain. Symptoms of ciguatera include a range of gastrointestinal, neurological and cardiovascular disturbances. This review examines progress in our understanding of ciguatera from the work of Banner in the late 1950s to the present. Similarities and differences in ciguatera in the Pacific Ocean, Indian Ocean and Caribbean Sea are highlighted, and future research directions are suggested. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：97 / 106

页数：10

共 65 条

[51]

POLI MA, 1986, MOL PHARMACOL, V30, P129

[52] Ciguatera in Reunion Island (SW Indian Ocean): Epidemiology and clinical patterns [J].

Quod, JP ;

Turquet, J .

TOXICON, 1996, 34 (07) :779-785

[53]

RANDALL JOHN E., 1958, BULL MARINE SCI GULL AND CARIBBEAN, V8, P236

[54]

RAYNER MD, 1972, FED PROC, V31, P1139

[55] SYNTHETIC STUDIES TOWARD CIGUATOXIN - STEREOCONTROLLED CONSTRUCTION OF THE KLM RING FRAGMENT [J].

SASAKI, M ;

INOUE, M ;

TACHIBANA, K .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (04) :715-717

[56] Isolation and structures of new ciguatoxin analogs, 2,3-dihydroxyCTX3C and 51-hydroxyCTX3C, accumulated in tropical reef fish [J].

Satake, M ;

Fukui, M ;

Legrand, AM ;

Cruchet, P ;

Yasumoto, T .

TETRAHEDRON LETTERS, 1998, 39 (10) :1197-1198

[57] THE STRUCTURE OF CTX3C, A CIGUATOXIN CONGENER ISOLATED FROM CULTURED GAMBIERDISCUS-TOXICUS [J].

SATAKE, M ;

MURATA, M ;

YASUMOTO, T .

TETRAHEDRON LETTERS, 1993, 34 (12) :1975-1978

[58]

SATAKE M, 1997, BIOSCI BIOTECH BIOCH, V60, P2103

[59]

SHARKEY RG, 1987, MOL PHARMACOL, V31, P273

[60]

Strachan LC, 1999, J PHARMACOL EXP THER, V288, P379

← 1 2 3 4 5 6 7 →