Understanding enzyme superfamilies - Chemistry as the fundamental determinant in the evolution of new catalytic activities

被引：232

作者：

Babbitt, PC ^{[1
]}

Gerlt, JA

机构：

[1] Univ Calif San Francisco, Sch Pharm, Dept Pharmaceut Chem, San Francisco, CA 94143 USA

[2] Univ Illinois, Sch Chem Sci, Dept Biochem, Urbana, IL 61801 USA

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 1997年 / 272卷 / 49期

关键词：

D O I：

10.1074/jbc.272.49.30591

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：30591 / 30594

页数：4

共 27 条

[21] Evolution of enzymatic activities: Multiple pathways for generating and partitioning a common enolic intermediate by glucarate dehydratase from Pseudomonas putida [J].

Palmer, DRJ ;

Gerit, JA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (42) :10323-10324

[22] Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold [J].

Perona, JJ ;

Craik, CS .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (48) :29987-29990

[23] ON THE ORIGIN OF ENZYMATIC SPECIES [J].

PETSKO, GA ;

KENYON, GL ;

GERLT, JA ;

RINGE, D ;

KOZARICH, JW .

TRENDS IN BIOCHEMICAL SCIENCES, 1993, 18 (10) :372-376

[24] RHIZOBIUM-MELILOTI LACKING MOSA SYNTHESIZES THE RHIZOPINE SCYLLO-INOSAMINE IN-PLACE OF 3-O-METHYL-SCYLLO-INOSAMINE [J].

RAO, JP ;

GRZEMSKI, W ;

MURPHY, PJ .

MICROBIOLOGY-UK, 1995, 141 :1683-1690

[25] The change in hydrogen bond strength accompanying charge rearrangement: Implications for enzymatic catalysis [J].

Shan, SO ;

Herschlag, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (25) :14474-14479

[26] OCTAHEDRAL COORDINATION AT THE HIGH-AFFINITY METAL SITE IN ENOLASE - CRYSTALLOGRAPHIC ANALYSIS OF THE MG-II-ENZYME COMPLEX FROM YEAST AT 1.9 ANGSTROM RESOLUTION [J].

WEDEKIND, JE ;

REED, GH ;

RAYMENT, I .

BIOCHEMISTRY, 1995, 34 (13) :4325-4330

[27] Identification of active site residues essential to 4-chlorobenzoyl-coenzyme A dehalogenase catalysis by chemical modification and site directed mutagenesis [J].

Yang, GA ;

Liu, RQ ;

Taylor, KL ;

Xiang, H ;

Price, J ;

DunawayMariano, D .

BIOCHEMISTRY, 1996, 35 (33) :10879-10885

← 1 2 3 →